Sir James Black, “The next major discoveries will be through a combination of astute clinical observation and simple chemistry”
This is the basis of our philosophy. Vastrata was established by seasoned biotech and pharma industry executives. Our approach is to identify drugs that work for the patient in that they are efficacious but suffer significant limitations; these being issues such as unwanted off-target side effects or non-optimal pharmacokinetic profiles. Many older generation drugs are very effective but would be much better tolerated or have better patient compliance if they were not blighted by significant side effects or pharmacokinetic issues. Once these drugs are identified together with their deficiencies, Vastrata creatively assesses what can be done to improve the said medicine and how easy it would be to improve the drug’s overall clinical profile.